دوره 4، شماره 2 - ( 3-1395 )                   جلد 4 شماره 2 صفحات 43-48 | برگشت به فهرست نسخه ها



DOI: 10.18869/acadpub.jhs.4.2.43

XML English Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Fayyaz-Movaghar A, Kamel-Mirmostafaee M T, Borhani T S. Probability Model of Allele Frequency of Alzheimer’s Disease Genetic Risk Factor . Iran J Health Sci. 2016; 4 (2) :43-48
URL: http://jhs.mazums.ac.ir/article-1-413-fa.html
Probability Model of Allele Frequency of Alzheimer’s Disease Genetic Risk Factor . علوم بهداشتی ایران. 1395; 4 (2) :43-48

URL: http://jhs.mazums.ac.ir/article-1-413-fa.html


چکیده:   (920 مشاهده)

Background and Purpose: The identification of genetics risk factors of human diseases is very important. This study is conducted to model the allele frequencies (AFs) of Alzheimer’s disease.

Materials and Methods: In this study, several candidate probability distributions are fitted on a data set of Alzheimer’s disease genetic risk factor. Unknown parameters of the considered distributions are estimated, and some criterions of goodness-of-fit are calculated for the sake of comparison.

Results: Based on some statistical criterions, the beta distribution gives the best fit on AFs. However, the estimate values of the parameters of beta distribution lead us to the standard uniform distribution.

Conclusion: The AFs of Alzheimer’s disease follow the standard uniform distribution.

متن کامل [PDF 742 kb]   (529 دریافت)    
نوع مطالعه: پژوهشي | موضوع مقاله: آمار زیستی
دریافت: ۱۳۹۵/۴/۶ | پذیرش: ۱۳۹۵/۴/۶ | انتشار: ۱۳۹۵/۴/۶

ارسال نظر درباره این مقاله : نام کاربری یا پست الکترونیک شما:
کد امنیتی را در کادر بنویسید

کلیه حقوق این وب سایت متعلق به می باشد.

طراحی و برنامه نویسی : یکتاوب افزار شرق

© 2015 All Rights Reserved | Iranian Journal of Health Sciences

Designed & Developed by : Yektaweb