en طب سالمندان Geriatrics پژوهشي Original Article <div style="text-align: justify;"><span style="font-size:14px;"><span style="font-family:Tahoma;"><span style="line-height:2;"><strong>Background and Purpose</strong>: Family caregivers play a crucial role in the long-term care system by providing the most supportive services to frail elderly individuals. Previous studies indicate that higher self-efficacy and certain personality traits are associated with reduced caregiver burden. The present study aimed to examine the association between self-efficacy and personality traits with caregiver burden among family caregivers of frail elderly residents living in Garmeh County, North Khorasan Province, Iran, in 2025.<br> <strong>Materials and Methods</strong>: This cross-sectional study was conducted on 243 family caregivers selected through a two-stage random sampling method. Data were collected using a demographic information form, the 17-item general self-efficacy scale (GSE-17), the caregiver burden inventory (CBI), and the 10-item personality inventory (TIPI). Data were analyzed in SPSS software, version 26 using independent t-tests, analysis of variance (ANOVA), Pearson correlation, and multiple linear regression, with a significance level at P&le;0.05.<br> <strong>Results</strong>: The mean age of the caregivers was 51.6&plusmn;11.3 years, with 90.5% female and 76.1% married. A significant negative correlation was found between self-efficacy and caregiver burden (r=-0.56, P<0.001), as well as between the personality dimensions of extraversion (r=-0.67, P&le;0.05) and openness to experience (r=-0.70, P&le;0.05) with caregiver burden. Multiple linear regression identified history of psychiatric visit (&beta;=-0.31, P<0.05), general self-efficacy (&beta;=-0.10, P<0.05), extraversion (&beta;=-0.16, P=0.05), openness to experience (&beta;=-0.32, P<0.05), and conscientiousness (&beta;=-0.14, P=0.05) as significant predictors of caregiver burden.<br> <strong>Conclusion</strong>: The findings revealed a significant inverse association between self-efficacy and caregiver burden, suggesting that enhancing self-efficacy may reduce caregiver burden. However, interventional studies are needed to confirm this association. Moreover, designing supportive interventions tailored to caregivers&rsquo; personality traits is recommended to reduce caregiver burden and promote family wellbeing effectively.</span></span></span></div> Self-efficacy, Personality, Caregiver burden, Caregivers, Frailty, Aged 35 46 http://jhs.mazums.ac.ir/browse.php?a_code=A-10-1227-1&slc_lang=en&sid=1 Sara Naseripoor Naseripoor1387@gmail.com 100319475328460014558 0009-0007-4694-9579 No Department of Geriatric Health, School of Nursing and Midwifery, Mazandaran University of Medical Sciences, Sari, Iran. Abdolhakim Jorbonyan hakim.jrm@gmail.com 100319475328460014559 100319475328460014559 No Department of Geriatric Health, School of Nursing and Midwifery, Mazandaran University of Medical Sciences, Sari, Iran. Mahmood Moosazadeh mmoosazadeh1351@gmail.com 100319475328460014560 100319475328460014560 No Gastrointestinal Cancer Research Center, Non-communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran. Ehteram Sadat Ilali paradis2082000@yahoo.com 100319475328460014561 100319475328460014561 Yes Department of Geriatric Health, School of Nursing and Midwifery, Mazandaran University of Medical Sciences, Sari, Iran.