Iranian Journal Of Health Sciences

fa Comparison between Revascularization and Optimal Medical Therapy in Patients with Stable Angina Pectoris بهداشت Health پژوهشي Original Article Background and Purpose: Regarding usefulness of revascularization versus optimal medical therapy in patients with stable angina pectoris, data are challenging. The aim of this 12-month follow-up study was to compare the survival benefit associated with revascularization versus optimal medical therapy on the patients with stable angina pectoris. Materials and Methods: A prospective clinical study was conducted on 181 patients with stable angina pectoris or an evidence of myocardial ischemia that underwent coronary arteriography. Patients with left main or left main equivalent were excluded from our study. Of these patients, 57 received full medical therapy alone, 79 were assigned to the percutaneous coronary intervention (PCI) and 45 to the coronary artery bypass graft (CABG) group. The patients were compared for primary outcomes including cardiac death and non-fatal myocardial infarction and secondary outcomes including disabling angina by chi-square and Fisher’s exact test. Results: After 12 months, cardiac death occurred in 8.8% of patients in the medical group and 0.0% of patients in the PCI and CABG group. This was statistically significant (P = 0.004). Disabling angina occurred in 23.1% of patients in the medical group, 17.7% of patients in the PCI group, and 15.5% of patients in CABG group (P = 0.349). Cerebrovascular accident occurred in 1.9% of patients in the medical group, 1.3% of patients in the PCI group, and 6.7% of patients in CABG group (P = 0.167). These were not statistically significant. Conclusion: Revascularization compared with the optimal medical therapy may be a better strategy in reducing cardiovascular mortality in patients with stable angina pectoris and suitable coronary anatomy. Coronary Disease, Prognosis, Revascularization, Everolimus, Stent 71 80 http://jhs.mazums.ac.ir/browse.php?a_code=A-10-279-3&slc_lang=fa&sid=1 Maryam Nabati dr.Mr.Nabati@gmail.com 10031947532846004672 10031947532846004672 Yes Mazandaran University of Medical Sciences, Sari, Iran Ehsan Vazirian 10031947532846004673 10031947532846004673 No Mazandaran University of Medical Sciences, Sari, Iran Ali Ghaemian 10031947532846004674 10031947532846004674 No Mazandaran University of Medical Sciences, Sari, Iran Jamshid Yazdani 10031947532846004675 10031947532846004675 No Mazandaran University of Medical Sciences, Sari, Iran Maryam Hosseinzadeh 10031947532846004676 10031947532846004676 No Mazandaran University of Medical Sciences, Sari, Iran