fa مدیریت بیمارستان Hospital Management پژوهشي Original Article <div style="text-align: justify;"><strong>Background and purpose:</strong> The insecticidal potential of <em>Carica papaya </em>(male and female species), and <em>Spondias mombin</em> were tested against the developmental stages of the malaria vector; <em>Anopheles gambiae</em> in the laboratory at an ambient condition.<br> <strong>Materials and Methods: </strong>Methanolic leaves extracts of <em>S. mombin</em> and <em>C. papaya</em> (male and female species) were carried out using cold extraction method. The extracts were evaporated and concentrated using a rotary evaporator under low pressure to make solvent-free. The <em>An. </em><em>gambiae</em> larvae and pupae were exposed to 0.1, 0.2, 0.3, 0.4, and 0.5% concentrations of the plant methanolic extracts for 24 hours and their mortality was recorded.<br> <strong>Results: </strong>Results indicated that <em>C. papaya</em> (male species) caused significantly higher mortality of the <em>An. gambiae</em> larvae and pupae than the other plant extract tested (p< 0.05). It caused 100% larval mortality and 95% pupal mortality at 0.5% concentration. However, it was observed that the larvae were more susceptible to the extracts of all the plants tested. Data were analyzed using Analysis of Variance and log probit analysis.<br> <strong>Conclusion: </strong>All the three medicinal plants screened in this work showed high potency to induce mortality of both the larval and pupal stages of the malaria vector and could consequently be used to reduce malaria prevalence in the endemic areas of Nigeria.<br> &nbsp;</div> Carica papaya, Spondias mombin, Anopheles gambiae, Mortality, Malaria 1 9 http://jhs.mazums.ac.ir/browse.php?a_code=A-10-764-2&slc_lang=fa&sid=1 Kayode David Ileke 10031947532846007361 10031947532846007361 No Akure, Ondo State, Nigeria Jacobs Mobolade Adesina moboladesina@rugipo.edu.ng 10031947532846007362 10031947532846007362 Yes Owo, Ondo State, Nigeria Adebimpe Olabisi Adeoye 10031947532846007363 10031947532846007363 No Ondo State, Nigeria Isaac Omotayo Olabimi 10031947532846007364 10031947532846007364 No Akure, Ondo State, Nigeria