en مديريت خدمات بهداشتي و درماني Management of health care services پژوهشي Original Article <div style="text-align: justify;">&nbsp;<strong>Background and Purpose</strong>: Currently, the high prevalence of COVID-19 and increased workload in hospitals has posed a threat to the physical, mental, and emotional health of nurses. The present study was an attempt to investigate the workload and its relationship with job stress of nurses in COVID-19 reference hospitals in southern Iran.<span dir="RTL"></span><br> <strong>Methods</strong>: This descriptive-analytical and cross-sectional study was conducted in 2021 on 431 nurses from COVID-19 reference hospitals in southern Iran. Data collection tools included the NASA workload and OSIPOW job stress standard questionnaires. Data were analyzed using t-test, ANOVA, and Pearson correlation coefficient in SPSS₂₃ Software and at a significance level of 0.05<strong><span dir="RTL"></span></strong><br> <strong>Results</strong>: The mean age and work experience of the nurses participating in the study were 31.03&plusmn;5.23 and 6.42&plusmn;4.61, respectively. The mean scores of the workload and job stresses were 83.64 <span dir="RTL">&plusmn;</span> 17.24 (of 100) and 236.68 <span dir="RTL">&plusmn;</span> 16.54 (of 300), respectively. Mental load dimension (85.81 <span dir="RTL">&plusmn;</span>19.31, of 100) among workload dimensions and role workload dimension (43.62 <span dir="RTL">&plusmn;</span> 19.14, of 50) among job stress dimensions had the highest mean score. Thus, there was found a statistically significant relationship between workload and job stress of nurses (P₌ 0.04, r₌ 0.19).<br> <strong>Conclusion</strong>: Workload and job stress of the studied nurses were estimated at a high level. There was a significant positive correlation between these two variables, and increasing workload resulted in an increase in job stress.<span dir="RTL"></span><br> <span dir="RTL"></span><span dir="RTL"></span></div> Workload, Job Stress, Nurses, COVID-19 1 11 http://jhs.mazums.ac.ir/browse.php?a_code=A-10-645-11&slc_lang=en&sid=1 Ali Reza Yusefi علی رضا یوسفی alirezayusefi67@gmail.com 10031947532846008175 10031947532846008175 Yes Department of Public Health, School of Health, Jiroft University of Medical Science, Jiroft, Iran استادیار Parnian Nikmanesh پرنیان نیک منش nikmaneshp.n@gmail.com 10031947532846008176 10031947532846008176 No Department of Health Services Management, School of Management and Medical Information, Iran University of Medical Sciences, Tehran, Iran دانشکده مدیریت دانشگاه علوم پزشکی ایران Shima Bordbar شیما بردبار shima_bordbar90@yahoo.com 10031947532846008177 10031947532846008177 No Department of Health Services Management, School of Management and Medical Information, Shiraz University of Medical Sciences, Shiraz, Iran. گروه مدیریت خدمات بهداشتی درمانی، مرکز تحقیقات منابع انسانی سلامت، دانشگاه علوم پزشکی شیراز، شیراز، ایران Mohammad Khammarnia محمد خمرنیا m_khammar1985@yahoo.com 10031947532846008178 10031947532846008178 No Health Promotion Research Center, Zahedan University of Medical Sciences, Zahedan, Iran. دانشگاه علوم پزشکی زاهدان Zahra Kavosi زهرا کاوسی zhr.kavosi@gmail.com 10031947532846008179 10031947532846008179 No Department of Health Services Management, School of Management and Medical Information, Shiraz University of Medical Sciences, Shiraz, Iran. گروه مدیریت خدمات بهداشتی درمانی، مرکز تحقیقات منابع انسانی سلامت، دانشگاه علوم پزشکی شیراز، شیراز، ایران