en آموزش بهداشت Health Education پژوهشي Original Article <div style="text-align: justify;"><span style="font-size:14px;"><span style="font-family:Tahoma;"><strong>Background and Purpose:</strong> Stress, academic failure, and low academic achievement of learners are among the major problems in their academic lives and the education system of each country. The present study aimed to investigate the mediating role of perceived academic stress in relationships of self-compassion and self-regulation with academic well-being in female students in Kermanshah City, Iran.&nbsp;<br> <strong>Materials and Methods:</strong> The research method was descriptive-correlational. The statistical population included all the female senior high school students of Kermanshah, within the 2020-2021 academic years. The random cluster sampling method was employed to select 216 students who completed the academic well-being, self-compassion, self-regulation, and perceived academic stress questionnaires. Path analysis and bootstrap method were adopted to evaluate the proposed model and test indirect relationships, respectively.&nbsp;<br> <strong>Results:</strong> The results indicated that all direct paths were significant (P<0.001), except for the path from self-compassion to academic well-being. The relationships of indirect paths were made significant through the mediating role of perceived academic stress in academic well-being (P<0.01).&nbsp;<br> <strong>Conclusion:</strong> According to the research results, perceived academic stress had a mediating role in the relationship between self-compassion and self-regulation with academic well-being in students; thus, it can be useful for developing and designing specific plans to prevent academic failure and improving academic well-being of students.</span></span><br> &nbsp;</div> <span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:Calibri,sans-serif"><span style="font-size:12.0pt"><span style="font-family:"Times New Roman",serif"></span></span></span></span></span> Psychological well-being, Self-compassion, Self-control, Stress, Students 29 36 http://jhs.mazums.ac.ir/browse.php?a_code=A-10-911-1&slc_lang=en&sid=1 Zahra Shirmohammadi زهرا شیرمحمدی shirmohamadzr@gmail.com 10031947532846009525 10031947532846009525 No Department of Psychology, Ahvaz Branch, Islamic Azad University, Ahvaz, Iran. گروه روان‌شناسی، واحد اهواز، دانشگاه آزاد اسلامی، اهواز، ایران Zahra Eftekhar Saadi زهرا افتخار صعادی zeftekharsaadi@gmail.com 10031947532846009526 10031947532846009526 Yes Department of Psychology, Ahvaz Branch, Islamic Azad University, Ahvaz, Iran. Marzieh Talebzadeh Shoushtari مرضیه طالب زاده شوشتری talebzademarzieh@gmail.com 10031947532846009527 10031947532846009527 No Department of Psychology, Ahvaz Branch, Islamic Azad University, Ahvaz, Iran. گروه روان‌شناسی، واحد اهواز، دانشگاه آزاد اسلامی، اهواز، ایران