Volume 5, Issue 4 (Autumn 2017)                   Iran J Health Sci 2017, 5(4): 10-25 | Back to browse issues page

XML Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Mortazavi S, Norozi Fard P. Risk Assessment of Non-Carcinogenic Effects of Heavy Metals from Dez River Fish. Iran J Health Sci. 2017; 5 (4) :10-25
URL: http://jhs.mazums.ac.ir/article-1-514-en.html
Malayer University, Malayer, Iran , mortazavi.s@gmail.com
Abstract:   (2385 Views)
Background and purpose: Considering the many benefits of fish in the food basket, it is essential to assess its health risk. The purpose of this study was to examine the risk assessment effects of heavy metals from Dez river fish.
Materials and Methods: In order to determine the concentration of heavy metals in the edible parts of fish, 80 samples were caught from the local species of Dez River, and after the bioassay, they were digested using the combination of 1:4 perchloric acid and nitric acid; afterwards, the concentration of heavy metals was measured by means of atomic absorption spectrometry.
Results: The results showed that there was a positive correlation between accumulating metals and condition factor, especially with regard to zinc and cadmium; this correlation was more likely to be observed for the Capoeta trutta species. Also, comparing the daily and weekly intake of heavy metals with the rate limits of PTDI and PTWI has shown that the absorption value of metals were considerably lower than the specified limit.
 Conclusion: The high level of CRlim showed safe consumption of fish in Dez River considering the potential health risk. Zinc and cadmium had also the highest share percent in finding out the TTHQ index. Also, the Target Hazard Quotient and Total Target Hazard Quotient were not higher than the one for all of the studied metals and species. The Capoeta trutta and Carasobarbus luteus species had the most and least amounts of TTHQ index. Finally, comparing the means of metal concentrations with standard ones has shown that the concentrations of zinc and cadmium were higher than the United Kingdom Ministry of Agriculture Fisheries and Food, Food and Drug Administer, Food and Agriculture Organization, FAO/WH limits and the international standards of European Commission and National Health and Medical Research Council, respectively.

Full-Text [PDF 967 kb]   (813 Downloads)    
Type of Study: Original Article | Subject: Environmental Health

1. Moka WJ, Senoo Sh, Itoh T, Tsukamasa Y, Kawasaki K-I, Masashi A. Assessment of concentrations of toxic elements in aquaculture food products in Malaysia. Food Chemistry 2012; 133(4): 1326–32. [DOI:10.1016/j.foodchem.2012.02.011]
2. Copat Ch, Arena G, Fiore M, Ledda C, Fallico R, Sciacca S, Ferrante M. Heavy metals concentrations in fish and shellfish from eastern Mediterranean Sea: Consumption advisories. Food and Chemical Toxicology 2013; 53: 33–7. [DOI:10.1016/j.fct.2012.11.038]
3. Hauser-Davis RA, Bordon IC, Oliveira TF, Ziolli RL. Metal bioaccumulation in edible target tissues of mullet (Mugil liza) from a tropical bay in Southeastern Brazil. Trace Elements in Medicine and biology 2016; 36: 38–43. [DOI:10.1016/j.jtemb.2016.03.016]
4. Shahbazi Y, Ahmadi F, Fakhari F. Voltammetric determination of Pb, Cd, Zn, Cu and Se in milk and dairy products collected from Iran: An emphasis on permissible limits and risk assessment of exposure to heavy metals. Food Chemistry 2016; 192: 1060–67. [DOI:10.1016/j.foodchem.2015.07.123]
5. Hussein A, Khaled A. Determination of metals in tuna species and bivalves from Alexandria, Egypt. The Egyptian Journal of Aquatic Research 2014; 40(1): 9–17. [DOI:10.1016/j.ejar.2014.02.003]
6. Gu Y-G, Lin Q, Wang X-H, Du F-Y, Yu Z-L, Huang H-H. Heavy metal concentrations in wild fishes captured from the South China Sea and associated health risks. Marine Pollution Bulletin 2015; 96(1-2): 508–12. [DOI:10.1016/j.marpolbul.2015.04.022]
7. Canli M, Ay O, Kalay M. Levels of heavy metals (Cd, Pb, Cu, Cr and Ni) in tissue of Cyprinus carpio, Barbus capitoand Chondrostoma regium from the Seyhan River, Turkey. Turkish Journal of Zoology 1998; 22(2): 149-57.
8. Turkmen A, Turkmen M, Tepe Y, Cekic M. Metals in tissues of fish from Yelkoma Lagoon, Northeastern Mediterranean. Environmental Monitoring and Assessment 2010; 168: 223- 30. [DOI:10.1007/s10661-009-1106-3]
9. Djedjibegovic J, Larssen T, Skrbo A, Marjanovic A, Sober M. Contents of cadmium, copper, mercury and lead in fish from the Neretva river (Bosnia and Herzegovina) determined by inductively coupled plasma mass spectrometry (ICP-MS). Food Chemistry 2012; 131(2): 469–76. [DOI:10.1016/j.foodchem.2011.09.009]
10. Fathi HB, Othman MS, Mazlan AG, Arshad A, Amin SMN, Simon KD. Trace Metals in Muscle, Liver and Gill Tissues of Marine Fishes from Mersing, Eastern Coast of Peninsular Malaysia: Concentration and Assessment of Human Health Risk. Asian Journal of Animal and Veterinary Advances 2013; 8(2): 227-36. [DOI:10.3923/ajava.2013.227.236]
11. Luna-Porres MY, Rodríguez-Villa MA, Herrera-Peraza EF. Potential Human Health Risk by Metal (loid)s, 234, 238U and 210Po due to Consumption of Fish from the "Luis L. Leon" Reservoir (Northern México). International Journal of Environmental Research and Public Health 2014; 11(7): 6612-38. [DOI:10.3390/ijerph110706612]
12. Gu SY-G, Huanga H-H, Lin Q. Concentrations and human health implications of heavy metals in wild aquatic organisms captured from the core area of Daya Bay's Fishery Resource Reserve, South China Sea. Environmental Toxicology and Pharmacology 2016; 45: 90–4. [DOI:10.1016/j.etap.2016.05.022]
13. Hoseini SM, Mirghaffari N, Mahbobi Soufiani N, Hoseini SV. Risk assessment of Mercury resulting from Consumer white fish of Caspian Sea (Rutilus frisii kutum) in Mazandaran province. Fish Sci 2011; 64(3): 243-57. URL: http://fa.journals.sid.ir/ViewPaper.aspx?id=148900. [In Persian]
14. Mardoukhi S, Hosseini SV, Hosseini SM. Risk to consumers from mercury in croaker (Otolithes ruber), from the Mahshahr port. Biology 2013; 2(3): 43-55. URL: http://fa.journals.sid.ir/ViewPaper.aspx?id=218456. [In Persian]
15. Solgi E. Risk assessment of non-carcinogenic effects of lead, cadmium, and zinc in Cyprinus carpio from Zarivar wetland. J Health Field, 2015; 2(4): 18-26. URL: http://journals.sbmu.ac.ir/jhf/article/view/7575.[In Persian]
16. Banagar G, Alipour H, Hasanpour M, Gholmohammadi S. Assessment of Human Health Risk for cadmium and lead in muscle of Liza auratus and Liza Saliens from Gorgan Gulf. Journal of Wetland Ecobiology, 2015; 7 (2):33-42.URL: http://jweb.iauahvaz.ac.ir/article-1-326-fa.html. [In Persian]
17. Banagar G, Alipour H, Hassanpour M, Golmohammadi S. Estimation of Daily Intake and Potential Risk of Chromium, Lead and Cadmium in Consumers of Common carp and Zander from Gorgan Gulf. Zanco Journal of Medical Sciences, 2015; 16 (49):22-31. URL: http://zanko. muk.ac.ir/article-1-80-fa.html. [In Persian]
18. Sadeghi Bajgiran S, Pourkhabbaz A, Hasanpour M, Sinka Karimi M. A study on Zinc, Nickel, and Vanadium in fish muscle of Alosa caspia and Sander lucioperca and food risk assessment of its consumption in the southeast of the Caspian Sea. Iranian Journal of Health and Environment, 2016; 8 (4):423-432. URL: http://ijhe.tums.ac.ir/article-1-5440-fa.html.[In Persian]
19. Kheirou N, Dadalhi Sohrab A. Concentrations of heavy metals in sediments and grypus (Barbus grypus) in the Arvandrood. Environ Sci Technol 2010; 12(2): 123-31. URL:http://www.magiran.com/magtoc.asp?mgID=2442&Number=45. [In Persian]
20. Yap CK, Ismail A, Cheng WH, Tan SG. Crystalline style and tissue redistribution in Perna viridis as indicators of Cu and Pb bioavailabilities and contamination in coastal waters. Ecotoxicology and Environmental Safety 2006; 63(3): 413-23. [DOI:10.1016/j.ecoenv.2005.02.005]
21. Schreck CB, Moyle PB. Methods for fish Biology, American Fisheries Society, Bethesda, MD, USA; 1990.
22. Omar WA, Zaghloul KhH, Abdel-Khalek, AA, Abo-Hegab S. Genotoxic effectes of metal pollution in two fish species, Oreochromis niloticus and Mugil cephalus, from highly degraded aquatic habitats. Mutation Research 2012; 46 (1): 7-14. [DOI:10.1016/j.mrgentox.2012.01.013]
23. Shaheen N, Irfan NMd, Nourin Khan I, Islama S, Islam MdS, Ahmed MdK. Presence of heavy metals in fruits and vegetables: Health risk implications in Bangladesh. Chemosphere 2016; 152: 431-38. [DOI:10.1016/j.chemosphere.2016.02.060]
24. FAO. Fishery and aquaculture statistics. Yearbook 2010. FAO, Rome, pp 1–107. Available from: http://www.fao. org/ fishery/ publications/yearbooks/en; 2012.
25. USEPA, United States Environmental Protection Agency. Human health evaluation manual, supplemental guidance: Standard default exposure factors. OSWER Directive 9285 6-03 Washington, DC; 1991.
26. USEPA, United States Environmental Protection Agency. United States Environmental Protection Agency, Risk assessment guidance for superfund. Volume 1: Human health evaluation manual (Part A). Interim Final, Office of Emergency and Remedial Response, USEPA, Washington, DC, 20450; 1989.
27. HHS: U.S. Department of Health and Human Services Public Health Service (HHS). Agency for Toxic Substances and Disease Registry Division of Health Assessment and Consultation Atlanta, Georgia 30333, Health Consultation, Fish Sampling in Silver Creek Analysis of Metals and Potential Health Impacts SILVER CREEK TAILINGS PARK CITY, SUMMIT COUNTY, UTAH EPA FACILITY ID: UTD980951404, OCTOBER 27; 2004.
28. Pourgholam R, Nasrallah zadeh Savari H, Rezaie M, Varedi SE. Review some heavy metal accumulation and health risk assessment in muscle tissue two species of white commercial fish (Rutilus frisii kutum) and narrow muzzle mullet (Liza saliens) Caspian Sea. Journal of Marine Science and Technology 2012; 7(4): 67-74. URL: http://journals.iau.ir/article_522157.html. [In Persian]
29. FAO. Compilation of legal limits for hazardous substance in fish and fishery products (Food and Agricultural Organization). FAO fishery circular, No. 464; 1983. p. 5–100.
30. Hassanpour M, Rajaei G, SinkaKarimi M, Ferdosian F, Maghsoudloorad R. Determination of Heavy Metals (Pb, Cd, Zn and Cu) in Caspian kutum (Rutilus frisii kutum) from Miankaleh International Wetland and Human Health Risk. Journal of Mazandaran University of Medical Sciences 2014; 24 (113) :163-170. URL: http://jmums.mazums.ac.ir/article-1-3801-en.html. [In Persian]
31. Maher WA. Trace metal concentrations in marine organisms from St. Vincent Gulf, South Australia. Water, Air and Soil Pollution 1986; 29(1): 77-84. [DOI:10.1007/BF00149330]
32. Elnabris KJ, Muzyed ShK, El-Ashgar NM. Heavy metal concentrations in some commercially important fishes and their contribution to heavy metals exposure in Palestinian people of Gaza Strip (Palestine). The Association of Arab Universities for Basic and Applied Sciences 2013; 13: 44–51. [DOI:10.1016/ j.jaubas. 2012. 06.001]
33. Darmono D, Denton GRW, Heavy metal concentrations in the banana prawn, Penaeus merguiensis, and leader prawn, P. monodon, in the Townsville Region of Australia. Bulletin of Environmental Contamination and Toxicology 1990; 44(3): 479-86. [DOI:10.1007/BF01701233]
34. Radojevi M, Bashkin VN. Practical Environmental Analysis, the Royal Society of Chemistry. UK; 1999. p. 466.
35. Dural M, Go¨ksu M, O¨zak A. Investigation of heavy metal levels in economically important fish species captured from the Tuzla lagoon. Food chemistry 2007; 102(1): 415–21. [DOI:10.1016/j.foodchem.2006.03.001]
36. EC. European Community. Commission Regulation No 78/2005 (pp. L16/43–L16/45). Official Journal of the European :union: (20.1.2005); 2005.
37. FAO/WHO. Evaluation of certain food additives and the contaminants mercury, lead and cadmium, WHO Technical Report, Series No. 505; 1989.
38. Institute of Standards and Industrial Research of Iran. Food and feed-maximum limit of heavy metals. Standard No. 12968.Tehran: Institute of Standards and Industrial Research of Iran; 2010.
39. Merian E. Metals and their Compounds in the Environment Occurrence, Analysis and Biological Relevance, Weinheim: VCH 704; 1991.
40. Mohammadi M, Askari Sari A, Khodadadi M. The of amount Cd and Pb in muscle and liver grypus (Barbus grypus) in the Dez River. Wetland, Islamic Azad University of Ahvaz 2010; 4: 91-6. URL:http://fa. journals.sid.ir/ViewPaper.aspx?id=129742. [In Persian]
41. Beheshti M, Askari Sari A, Velayatzadeh M. Assessment of Heavy Metals Concentration of Fish (Liza abu) in Karoon River, Khouzestan Province. Water and wastewater 2012; 3: 125-33. URL:http: // www. wwjournal. ir/article _1945. html. [In Persian]
42. Askary sary A, Velayatzadeh M, Khodadadi M, Kazemian M. Mercury, cadmium and lead contents of tissues of Liza abu fish in the Dez and Bahmanshir Rivers, Iran. Journal of School of Public Health and Institute of Public Health Research, 2012; 9 (3):1-12. URL: http://sjsph.tums.ac.ir/article-1-41-fa.html. [In Persian]
43. Musavi-Nadushan R, Salimi L, Zaheri-AbdehvandAbvehvand L. Determining the concentrations of nickel, lead and cadmium in Barbus grypus of Dez River, Iran. Journal of Mazandaran University of Medical Sciences, 2014; 23 (110):232-236. URL: http://jmums.mazums.ac.ir/article-1-3400-fa.html. [In Persian]
44. Zaheri-Abdehvand L, Mousavi Nadoshan R, Salami L, Nabigahfarokhi Kh. Concentrations of Nickel, Lead and Cadmium in Barbus xanthopterusin Dez River. Journal of Mazandaran University of Medical Sciences 2015; 25(123): 197-202. URL: http://jmums.mazums.ac.ir/browse.php?a_code=A-10-5029-52&slc_lang=fa&sid=1&sw=. [In Persian]
45. Mojoudi N, mojoudi F, Kafilzadeh F. Investigate of accumulation the heavy metals Cd, Pb, and Zn in liver and muscle tissues Capoeta trutta fish from Dez River, southwest Iran. Iranian Journal of Biotechnology, 2013; 3(8): 325-31.
46. Mohammadi M, Askary Sary A, Khodadadi M. Accumulation Variations of selected heavy metals in Barbus xanthopterus in Karoon and Dez Rivers of Khuzestan, Iran. Iranian Journal of Fisheries Sciences 2012; 11(2): 372-82. URL: http://en.journals.sid.ir/ViewPaper.aspx?ID=425582
47. Sekhar KC, Chary NS, Kamala CT, Raj DSS Rao AS. T5, 1001-1008; 2003.
48. Uttah C, Utth E, Ayanda I. Environmental Quality Assessment of Anthropogenically Impacted Estuary using Fish Genera Composition, Tissue Analysis, and Condition Factor. The Pacific Journal of Science and Technology 2012; 13 (2): 537-42. Available from: http://www. akamaiuniversity.us/PJST.htm
49. Mukherjee DP, Bhupander K. Assessment of Arsenic, Cadmium and Mercury Level in Commonly Consumed Coastal Fishes from Bay of Bengal, India. Food Science and Quality Management 2011; 2: 19-31. Available from: http://www. iiste.org/ Journals/index.php/FSQM/article/view/1055
50. Al Sayegh Petkovšek S, Mazej Grudnik Z, Pokorny B. Heavy metals and arsenic concentrations in ten fish species from the Šalek lakes (Slovenia): assessment of potential human health risk due to fish consumption. Environmental Monitoring and Assessment 2012; 184(5): 2647-62.
51. Bat L, Sahin F, Üstün F, Sezgin M. Distribution of Zn, Cu, Pb and Cd in the tissues and organs of Psetta maxima from Sinop Coasts of the Black Sea. Marine Science 2012; 2(5): 105–9.
52. Pourang N, Dennis JH, Ghourchian H. Distribution of heavy metals in Penaeus semisulcatus from Persian Gulf and possible role of metallothionein in their redistribution during storage. Environmental Monitoring and Assessment 2005; 100(1): 71-88.
53. Ateş A, Türkmen M, Tepe Y. Assessment of Heavy Metals in Fourteen Marine Fish Species of Four Turkish Seas. Indian Journal of Geo-Marine Sciences 2015; 44 (1): 49-55.URL: http://hdl.handle. net/123456789/ 34619
54. Wang X, Sato T, Xing B, Tao S. Health risks of heavy metals to the general public in Tianjin, China via consumption of vegetables and fish. Science of The Total Environment 2005; 350: 28-37.
55. Saha N, Mollah MZI, Alam MF, Safiur Rahman M. Seasonal investigation of heavy metals in marine fishes captured from the Bay of Bengal and the implications for human health risk assessment. Food Control 2016; 70: 110-18.
56. Ruelas-Inzunza J, Meza-Lópeza G, Páez-Osuna F. Mercury in fish that are of dietary importance from the coasts of Sinaloa (SE Gulf of California). Journal of Food Composition and Analysis, 2008; 21(3): 211–18.
57. Alipour H, Pourkhabbaz AR, Hassanpour, M. Assessing of heavy metal concentrations in the tissues of Rutilus rutilus caspicus and Neogobius gorlap from Miankaleh international wetland. Bulletin of Environmental Contamination and Toxicology 2014; 91 (5): 517-21.
58. Taweel A, Shuhaimi-Othman M, Ahmad AK. Assessment of heavy metals in tilapia fish (Oreochromis niloticus) from the Langat River and Engineering Lake in Bangi, Malaysia, and evaluation of the health risk from tilapia consumption. Ecotoxicology and Environmental Safety 2013; 93: 45-51.
59. Idriss AA, Ahmad AK. Heavy metal concentrations in fishes from Juru River, estimation of the health risk. Bulletin of Environmental Contamination and Toxicology 2015; 94(2): 204-8.
60. Hoseini SM, Mirghaffari N, Mahbubi Sufiani N, Hosseini SV, Ghasemi AF. Risk assessment of the total mercury in Golden gray mullet (Liza aurata) from Caspian Sea. International Journal of Aquatic Biology 2013; 1(6): 258-65. Available from: https://doaj.org/article/8811fb58e9f841a28362c38c0b1b2847
61. Velayat Zade M, Tabibzadeh M. Investigate and compare accumulation of heavy metals mercury, cadmium and lead in muscle and liver (Cyprinion macrostomus). Science and Technology Food 2011; 1: 27-33 (Persian). URL: http://fa.journals.sid.ir/ ViewPaper. aspx?id=143941
62. Kheirou N, Dadolahi sohrab A. Concentration of heavy metals in sediment and Barbus grypus in Arvandroud. International Journal of Environmental Science and Technology 2010. 12(2): 131-123. URL: http://www.magiran.com/magtoc.asp?mgID=2442&Number=45. [In Persian]
63. Bandani G, Khoshbavar Rostami H, Yelghi S, Shokrzadeh M, Nazari H. Concentration of heavy metals (Cd, Cr, Zn, and Pb) in muscle and liver tissues of common carp (Cyprinus carpio L., 1758) from coastal waters of Golestan Province . Iranian Scientific Fisheries Journal, 2011; 19 (4):1-10. URL: http://isfj.ir/article-1-125-fa.html . [In Persian]
64. Zalaghi F, Haieri Pour S, Askari Sari A. Evaluation of lead and cadmium concentrations in liver and muscle of Barbus (Barbus pectoralis) Karun River. Wetland Ecobiol 2011; 8: 68-75. URL:http://fa.journals.sid.ir/ViewPaper.aspx?id=155048. [In Persian]

Add your comments about this article : Your username or Email:

Send email to the article author

© 2019 All Rights Reserved | Iranian Journal of Health Sciences

Designed & Developed by : Yektaweb