Volume 1, Issue 3 (Autumn 2013)                   Iran J Health Sci 2013, 1(3): 43-50 | Back to browse issues page

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Dehghani M, Ahmadi M, Nasseri S. Photodegradation of the Antibiotic Penicillin G in the Aqueous Solution using UV-A Radiation. Iran J Health Sci. 2013; 1 (3) :43-50
URL: http://jhs.mazums.ac.ir/article-1-123-en.html
Department of Environmental Health Engineering, School of Health , mdehghany@sums.ac.ir
Abstract:   (31774 Views)

Background and purpose: Highly consumption of antibiotics and their entrance into the environment has increased concerns all over the world. These compounds enter to the environment through an incomplete metabolism and a considerable amount of them cannot be removed using usual waste filtration systems. Therefore, the present study aimed to investigate the feasibility of using ultraviolet radiation (UV-A) to remove penicillin G (PENG) from aqueous phase and determining its removal efficiency. Materials and Methods: The experiments were carried out in the batch mode. The samples were assessed in a 2-liter reactor. In order to investigate the effect of UV-A radiation on the removal rate of antibiotic penicillin G (PENG), the following parameters were studied. Three concentration levels of PENG antibiotic (10,25,and 45 mg/l) were exposed to UV-A at three pH levels (3,7,11) and were evaluated at four reaction times (30,60,90, and 120 min). Antibiotic penicillin G (PENG) was determined using HPLC instrument (Waters YL9100,USA) and results analyzed using factorial design software. Results: The finding demonstrated that antibiotic removal rate increased by decreasing pH and decreasing the initial concentration of antibiotic and increasing contact time. The maximum rate of penicillin G removal occurred in acidic pH (pH=3) is as much as 38%. All of the variables in the process have been statistically significant effect (p<0.001). Conclusion: Results showed that by reducing the pH, increasing contact time and reducing the antibiotic concentration, the removal rate increases. In conclusion, photodegradation process using UV-A may enhance the rate of penicillin G degradation in polluted water and could be used as a complementary step for other chemical and biological processes to remove penicillin G from the aqueous solution. Therefore, UV-A process in conjugate with the other processes is an appropriate method for reducing antibiotic penicillin G in polluted water resources.

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Type of Study: Original Article | Subject: Environmental Health

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